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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: FKBP51 mediates resilience to inflammation-induced anxiety through regulation of glutamic acid decarboxylase 65 expression in mouse hippocampus

Fig. 7

Subregional alterations in GAD65 expression in the hippocampus and amygdala in LPS-injected mice. Mouse brains were harvested 7 days after the injection of SAL or LPS for immunohistochemical analysis. A Representative immunofluorescent image of GAD65 (green) and DAPI (blue) staining in the hippocampal subregion of the ventral CA1 (vCA1, upper panel) and dorsal CA1 (dCA1, middle panel) as well as the amygdala (lower panel). B–D The area expressing GAD65 was quantified by calculating the ratio of their immunoreactive area to total number of DAPI in the stratum pyramidal (SP) layer of vCA1 (B), dCA1 (C), or central nucleus of the amygdala (CeA, D). Data are indicated as the mean ± SEM (n = 5 mice per group). *p < 0.05, **p < 0.01, and ***p < 0.001 for the comparison between two groups in an unpaired Student’s t test. Scale bar: 100 μm. SR: stratum radiatum, BLA: basolateral amygdala

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