Fig. 7

Nerve injury-induced Nav1.6 is expressed in TNF-α, IL-6-positive cells and ACC neurons. Double-immunofluorescence staining showing that A upregulated Nav1.6-IR (green) 7d post-SNI is co-localized with TNF-α- and IL-6-IR (red), and B Nav1.6-IR (red) is co-localized with NeuN (green), but not Iba1 (green) and GFAP (green) 7d post-SNI. Higher magnification micrographs from boxed areas are shown below each group. Scale bar = 50 μm. The fluorescence intensity curves for red and green from boxed areas are shown on the right side of each group