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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Astrocyte reactivation in medial prefrontal cortex contributes to obesity-promoted depressive-like behaviors

Fig. 3

High-fat diet and leptin knockout dramatically increase astrocyte reactivation. A Astrocyte morphology was measured by calculating (B) spreading area and number of interactions. The level of D-serine, glutamate, ATP, and GABA were also assessed in microdialysate from mPFC (C and D). (*p < 0.05, **p < 0.01, ***p < 0.001 compared with ND mice; ##p < 0.01, ###p < 0.001 compared with LM mice)

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