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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Astrocyte reactivation in medial prefrontal cortex contributes to obesity-promoted depressive-like behaviors

Fig. 5

Activating astrocytes in mPFC of resilient mice induces similar depressive-like behaviors compared with susceptible mice. A To assess the behavioral changes among different mice model, social interaction was performed under aggressor present and absent. B The anxiety behaviors of mice were evaluated by open-field test and elevated plus-maze, and C depressive behaviors of mice were investigated by tail suspension test, forced swim test, and sucrose preference test. To detect neuronal activities in mPFC, sIPSC and sEPSC (D) were recorded, and frequency and amplitude were calculated (E and F). (p < 0.05 was considered as significant difference)

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