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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Astrocyte reactivation in medial prefrontal cortex contributes to obesity-promoted depressive-like behaviors

Fig. 6

mPFC injection of GfaABC1D-hM4Di-AAV and CNO i.p treatment significantly inhibited astrocytes reactivity. Diagram of experimental design (A). Astrocyte response was detected by investigating activation related genes expression of isolated astrocyte (B). Astrocyte morphology was measured by calculating (C) spreading area and number of interactions. The level of D-serine, glutamate, ATP, and GABA were also assessed in microdialysate from mPFC (D). (*p < 0.05 compared with saline-treated mice)

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Journal of Neuroinflammation

ISSN: 1742-2094