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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Astrocyte reactivation in medial prefrontal cortex contributes to obesity-promoted depressive-like behaviors

Fig. 8

JNK–STAT3 signaling contributes to HFD-induced astrocytes reactivation. A Graphic illustration of the signaling pathway in astrocytes related to reactivation. B Astrocytes from ND and HFD mice were isolated by MACS and detected by flow cytometry. The astrocytes reactivation related membrane receptors (C) and intracellular modulators (D) were detected by Milliplex assay. E Astrocytes from saline and CNO-injected mice were isolated by MACS and detected by flow cytometry. The astrocytes reactivation related membrane receptors (F) and intracellular modulators (G) were detected by Milliplex assay. (*p < 0.05, ***p < 0.001 compared with ND mice; #p < 0.05, ##p < 0.001 compared with saline-treated mice)

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Journal of Neuroinflammation

ISSN: 1742-2094