Fig. 2

CSF secretion rate and hydrocephalus evaluation index after ICH-IVH and IVH. A Representative T2-weighted images and 3D reconstruction of lateral ventricles obtained on day 3 and day 7 in the IVH and ICH-IVH groups. B Quantification volumes of the lateral ventricle according to the related T2-weighted images (6 rats/group, one-way ANOVA). C Quantification of CSF secretion rates in sham, IVH and ICH-IVH rats at 3 and 7 days (6–8 rats/group, one-way ANOVA). D Representative images of immunofluorescence staining for laminin expression in arachnoid granules. Bar = 50 μm. E Number of hindlimb drops recorded for a walking task in which the rat walks over a rotating beam toward the home cage on a platform (6 rats/group, one-way ANOVA). F Testing for front grip strength at different time points (6 rats/group, one-way ANOVA). E mNSS (6 rats/group, one-way ANOVA). The results are presented as the means ± SDs; **p < 0.01 and *p < 0.05: sham group versus ICH-IVH group. #p < 0.05: sham group versus IVH group