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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: NLRP3 inflammasome-mediated choroid plexus hypersecretion contributes to hydrocephalus after intraventricular hemorrhage via phosphorylated NKCC1 channels

Fig. 3

Transcriptome and proteomic sequencing was performed to explore inflammation pathways activated after ICH-IVH in the choroid plexus. A Venn diagram showing RNA and protein sequencing. B Volcano map showing significantly changed genes identified by transcriptome sequencing between the sham group and ICH-IVH group. C Volcano map showing significantly changed genes identified by proteomic sequencing after ICH-IVH. D GO enrichment of transcriptome sequencing showing that the inflammatory response was upregulated after ICH-IVH. E KEGG pathway enrichment of transcriptome sequencing showed that NOD-like receptors were upregulated after ICH-IVH. F Heatmap of transcriptome sequencing showing the top 30 genes related to inflammation between the sham group and ICH-IVH group. (H) Heatmap of proteomic sequencing showing the top 30 proteins related to inflammation after ICH-IVH

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Journal of Neuroinflammation

ISSN: 1742-2094