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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: NLRP3 inflammasome-mediated choroid plexus hypersecretion contributes to hydrocephalus after intraventricular hemorrhage via phosphorylated NKCC1 channels

Fig. 4

NLRP3 inflammasome components were activated after ICH-IVH in the choroid plexus. A Western blot analysis of NLRP3 in the choroid plexus over time and statistical analysis of NLRP3 protein levels achieved at a maximum of 3 days after ICH-IVH (n = 5, 6 rats/sample, one-way ANOVA). B Representative images showing the choroid plexus AE2 location in ventricular systems; LV: lateral ventricle; 3 V: the third ventricle; the white arrow indicates the choroid plexus. Bar = 300 μm. C Representative fluorescence photomicrographs showing immunolabeling for NLRP3-positive cells in the choroid plexus 3 days after ICH-IVH (6 rats/group). Bar = 50 μm. The values are expressed as the means ± SDs; **p < 0.01; *p < 0.05

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