Fig. 2

CXCR2 expression is upregulated in monocytes in cerebrospinal fluid (CSF) of TBI patients post-operation, and correlated with the CXCR2 expression value on peripheral monocytes. A (Left) Flow cytometry results of CD11b⁺CD14⁺ monocyte subsets in CSF of TBI patients after surgery. (Right) Typical flow cytometry results of CXCR2 expression on CD14⁺ monocyte subsets in CSF of TBI patients on different days after surgery. B Proportion of CD14⁺ monocytes in CSF of TBI or non-TBI patients. The dashed line represents average proportion of CD14⁺ monocytes of non-TBI patients. **P < 0.01, TBI vs. non-TBI, determined by unpaired t test. C Proportion of CXCR2⁺ subsets in CD14⁺ monocytes in CSF of TBI or non-TBI patients. The dashed line represents average proportion of CXCR2⁺ subsets of non-TBI patients. **P < 0.01, TBI vs. non-TBI, determined by unpaired t test. D ΔMFI value of CXCR2 on CD14⁺ monocytes in CSF of TBI or non-TBI patients. The dashed line represents average ΔMFI value of CXCR2 of non-TBI patients. *P < 0.05, TBI vs. non-TBI, determined by unpaired t test. E Linear association of ΔMFI value of CXCR2 between monocytes in CSF and monocytes in peripheral blood of TBI patients. R² was determined by Pearson correlation. Data are presented as mean with SEM