Fig. 4
From: Increased levels of a pro-inflammatory IgG receptor in the midbrain of people with schizophrenia
FcGRT and FcGR3A, but not FcGR2B mRNA levels were increased in the midbrain from high-inflammation biotype schizophrenia cases. Midbrain FcGRT mRNA (a) and FcGR2B mRNA (c) levels were unchanged when comparing schizophrenia cases with control subjects. FcGR3A gene expression was increased in schizophrenia cases compared to control subjects (e). When separated by inflammatory biotype, FcGRT mRNA (b) and FcGR3A (f) mRNA levels were elevated in high-inflammation biotype schizophrenia cases when compared with both the low-inflammation biotype schizophrenia cases and control subjects. There was no difference in FcGR2B mRNA in the midbrain between high-inflammation biotype schizophrenia cases, low-inflammation biotype schizophrenia cases, and control subjects (d). *p < 0.05 **p < 0.01 ****p < 0.0001. Mean ± SEM