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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Drp1 activates ROS/HIF-1α/EZH2 and triggers mitochondrial fragmentation to deteriorate hypercalcemia-associated neuronal injury in mouse model of chronic kidney disease

Fig. 1

The increased calcium content in prefrontal cortical tissues of CKD mice leads to nerve injury. A FITC inulin clearance curve. B Mean mouse kidney weight. C Representative H&E, PAS, and Masson images of mouse kidney sections (scale bar = 50 μm). D The calcium content in mouse prefrontal cortical tissues. E The escape latency, the frequency of times entering the target quadrant, the time spent in the platform quadrant, and the total movement distance. F TUNEL-positive cells (apoptosis) in mouse prefrontal cortical tissues. G, Proportion of NeuN-positive cells in mouse prefrontal cortical tissues. N = 6. *p < 0.05; **p < 0.001

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