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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Aprepitant attenuates NLRC4-dependent neuronal pyroptosis via NK1R/PKCδ pathway in a mouse model of intracerebral hemorrhage

Fig. 7

Effects of NLRC4 knock down with siRNA on the level of C-Caspase-1 and neurological function at 24 h after ICH. A Representative western blot bands of NLRC4 and C-Caspase-1 after administration of NLRC4 siRNA, and B, C quantitative analyses of NLRC4 and C-Caspse-1; DF Modified Garcia test, forelimb placement test, corner turn test at 24 h after ICH. Data were represented as mean ± SD. # p < 0.05 vs Naïve + Scr siRNA, $ p < 0.05 vs ICH + Scr siRNA. One-way ANOVA, Tukey test, n = 6/group

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