Skip to main content
Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Macrophages in close proximity to the vitreoretinal interface are potential biomarkers of inflammation during retinal vascular disease

Fig. 5

Perivascular macrophage are CD206+ and exist within the Collagen IV vascular sheath. High resolution confocal immunofluorescence of CD31 (blue), GFP (green), CD206 (red), and Collagen IV (Col IV, white) from Tmem119GFP/+ retinal flatmounts. For all panels, the main image is the XY for a Z-plane defined by the thin white line in both the YZ plane to the right of the main image and the XZ plane to the bottom. At each white cross hair, a CD206+GFPneg macrophage is adjacent to a CD31+ superficial large retinal vessel within 5–10 microns of the retinal surface and within the Collagen IV+ vascular sheath. Scale bars are 10 microns. A–C Are representative images from 3 independently imaged mice from a single litter

Back to article page