Table 4 Clinical variables in patients according to change of CE
From: Systemic inflammatory markers of persistent cerebral edema after aneurysmal subarachnoid hemorrhage
Variable | Classified by baseline and follow-up SEBES grade | ||||
|---|---|---|---|---|---|
High-grade SEBES, baseline (N = 41) | Low-grade SEBES, baseline (N = 94) | p value†| |||
G4 (persistently poor, n = 21) | G3 (improved, n = 20) | G2 (worsened, n = 17) | G1 (persistently good, n = 77) | ||
Age (years) | 48.8 ± 11.2 | 47.3 ± 10.2 | 46.8 ± 14.9 | 55.7 ± 13.5 | < 0.01 |
Gender, male | 3 (14.3) | 4 (20.0) | 2 (11.8) | 22 (28.6) | 0.29 |
Race | 1.00 | ||||
 White | 15 (71.4) | 13 (65.0) | 12 (64.7) | 50 (64.9) |  |
 Black | 4 (19.0) | 5 (25.0) | 4 (23.5) | 18 (23.4) |  |
 Asian or others | 2 (9.5) | 2 (10.0) | 2 (11.8) | 9 (11.7) |  |
Risk factors and comorbidities | |||||
 Hypertension | 12 (57.1) | 16 (80.0) | 10 (58.8) | 52 (67.5) | 0.40 |
Dyslipidemia | 1 (4.8) | 4 (20.0) | 2 (11.8) | 9 (11.7) | 0.50 |
 Diabetes mellitus | 2 (9.5) | 1 (5.0) | 3 (17.6) | 13 (16.9) | 0.43 |
 Current smoking | 4 (19.0) | 8 (40.0) | 4 (23.5) | 34 (44.2) | 0.10 |
 Prior coronary artery disease | 1 (4.8) | 1 (5.0) | 2 (11.8) | 8 (10.4) | 0.72 |
 Prior stroke | 0 (0.0) | 1 (5.0) | 1 (5.9) | 9 (11.7) | 0.16 |
Clinical and radiographic severity of SAH on admission | |||||
 WFNS grade | 4 [3–5] | 4 [2–5] | 4 [2–5] | 2 [1–2.5] | < 0.01 |
 mFS grade | 3 [3–3] | 3.5 [3–4] | 3 [3–4] | 3 [3–3] | < 0.01 |
 IVH | 14 (66.7) | 16 (80.0) | 12 (70.6) | 47 (61.0) | 0.43 |
 Hydrocephalus | 17 (81.0) | 16 (80.0) | 12 (70.6) | 45 (58.4) | 0.11 |
Therapeutic intervention | |||||
 Coiling | 8 (38.1) | 6 (30.0) | 7 (41.2) | 22 (28.6) | 0.69 |