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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Transcriptome profiling of microRNAs reveals potential mechanisms of manual therapy alleviating neuropathic pain through microRNA-547-3p-mediated Map4k4/NF-κb signaling pathway

Fig. 3

Analysis of differentially expressed miRNAs in DRG between the MT and CCD groups. A Volcano plot of differentially expressed miRNAs. Red plots indicate upregulated miRNAs and green plots indicate downregulated miRNAs in the MT group compared with those in the CCD group. B Heat map of differentially expressed miRNAs. For each miRNA, red indicates upregulated and green indicates downregulated miRNAs. The darker the color, the higher would be the expression. C, D GO functional enrichment and KEGG pathway analysis were performed to identify potential pathways or biological processes associated with the mechanism of MT. The abscissa indicates the number of enriched target genes and − log10(P-value), and the ordinate indicates the top 30 GO enrichment or KEGG pathway terms. CCD chronic compression of dorsal root ganglion, DRG dorsal root ganglion, GO Gene Ontology, KEGG Kyoto Encyclopedia of Genes and Genomes, MT manual therapy

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Journal of Neuroinflammation

ISSN: 1742-2094