Transcriptome profiling of microRNAs reveals potential mechanisms of manual therapy alleviating neuropathic pain through microRNA-547-3p-mediated Map4k4/NF-κb signaling pathway

Table 2 List of miRNAs differentially expressed in DRG of CCD rats compared with sham rats

No.	MiRNA	Log₂ (fold change)	Regulation	P-value
1	miR-375-3p	4.903986176	Up	< 0.001
2	miR-449a-5p	2.592291784	Up	< 0.001
3	miR-21-5p	1.897166256	Up	0.031
4	miR-135a-5p	1.723550334	Up	< 0.001
5	miR-34c-3p	1.650507208	Up	0.007
6	miR-31a-5p	1.611819174	Up	0.009
7	miR-206-3p	1.513704055	Up	< 0.001
8	rmiR-34c-5p	1.493525558	Up	0.003
9	miR-144-5p	1.480404628	Up	0.035
10	miR-130b-5p	1.456294712	Up	0.004
11	miR-3559-5p	1.276851951	Up	0.030
12	miR-34b-5p	1.262181137	Up	0.036
13	miR-133a-5p	1.191435092	Up	0.026
14	miR-142-5p	1.158505314	Up	0.002
15	miR-1-3p	1.129191416	Up	0.017
16	miR-542-3p	1.059693765	Up	0.032
17	miR-296-5p	1.056567783	Up	0.029
18	miR-20a-5p	1.053024673	Up	0.001
19	miR-451-5p	1.035219621	Up	0.022
20	miR-96-5p	− 1.166135601	Down	0.003
21	miR-183	− 1.200157191	Down	0.036
22	miR-547-3p	− 6.675122118	Down	< 0.001