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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Flufenamic acid improves survival and neurologic outcome after successful cardiopulmonary resuscitation in mice

Fig. 8

Effects of FFA on neurological function in Trpm4−/− mice after CA/CPR. A Neurological function scores of survived mice from the WT, KO and KO (FFA) groups at 3 days and 7 days after ROSC. B The latency to drop from the accelerating rotarod. C Representative paths of mice during the open field test. D The total distance traveled in the open field test. E Representative swimming paths of mice during the probe trial. The latency to find the platform (F) and swimming distance (G) during the spatial exploration experiment. The percentage of time spent in the target quadrant (H) and platform crossovers (I) during the probe trial. J The swimming speed of mice in the Morris water maze test. *P < 0.05, **P < 0.01, ***P < 0.001 versus the WT group, n = 8. KO: vehicle-treated Trpm4−/− mice; KO (FFA): flufenamic acid-treated Trpm4−/− mice

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