Skip to main content

Table 3 Peripheral inflammation in the blood of PD patients and healthy controls

From: Brain microglia activation and peripheral adaptive immunity in Parkinson’s disease: a multimodal PET study

 

Control

n = 22

PD

n = 22

P

Total T cells/lymphocytes

73.24% ± 8.78%

72.95% ± 7.47%

0.976

Th1/total T cells

9.81% ± 2.42%

12.85% ± 3.19%

0.008*

Th2/total T cells

3.25% ± 2.51%

3.15% ± 1.46%

0.842

Th17/total T cells

1.65% ± 0.79%

2.10% ± 1.53%

0.743

IFNγ

6.30 ± 2.63

5.62 ± 2.35

0.375

TNFα

1.88 ± 0.38

1.92 ± 0.42

0.707

IL6

0.746 ± 0.462

0.659 ± 0.432

0.343a

IL8

7.02 ± 2.86

7.89 ± 2.82

0.320

IL10

0.083 ± 0.052

0.202 ± 0.195

0.002*a

IL12p70

0.078 ± 0.117

0.070 ± 0.049

0.762

IL22

0.605 ± 0.652

0.440 ± 0.354

0.921a

IL17A

0.395 ± 0.204

0.577 ± 0.352

0.045*

  1. P p-value, PD Parkinson’s disease, Th T helper cells
  2. *P < 0.05
  3. aCalculated with Mann–Whitney test