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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: The cytokine IL-27 reduces inflammation and protects photoreceptors in a mouse model of retinal degeneration

Fig. 3

IL-27 leads to higher retinal function. a Representative ERG waves for photopic stimulation at flash intensity − 1 log cd s/m2. b Scotopic and c photopic b-wave amplitudes are shown for the IL-27 injected rd10 mice compared with untreated and saline-injected mice using ERG recordings measured at age P25. Responses to three different flash intensities are shown. IL-27 increased b-wave amplitudes compared with saline and untreated mice. Statistical significance of p < 0.05 is marked with an asterisk (*) for IL-27 vs saline comparisons and a number sign (#) for IL-27 vs untreated comparisons. The average values for untreated mice are shown as circles (n = 10), saline injected as squares (n = 8), 10 ng IL-27 injected as triangles (n = 9), 20 ng IL-27 as inverted triangles (n = 11), and 40 ng IL-27 as diamonds (n = 12). Averages and standard error are shown

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