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Table 1 Summary of neurological involvement in COVID-19 patients in existing studies

From: COVID-19 and cognitive impairment: neuroinvasive and blood‒brain barrier dysfunction

Number of patients

Incidence of cognitive impairment

Other types of neurological symptoms

References

214

Headache, disturbance of consciousness, neuralgia, ataxia, acute cerebrovascular disease, seizures

[22]

29

59–65% (at 4 months)

Executive dysfunction (33%)

[25]

2103

61.5–80% (at 3 months)

[26]

53

61.5%

Hyposmia (26%), headache (21%), ischaemic stroke (11.1%), coordination deficits (74%), paresis (47%), abnormal reflex status (45%), sensory abnormalities (45%)

[27]

26

69.2%

Anosmia (34%), hyposmia (52%), hypogeusia (100%)

[28]

179

58.7% (at 2 months)

Impaired immediate verbal memory and learning (38%), delayed verbal memory (11.8%), verbal fluency (34.6%) and working memory (executive function) (6.1%)

[29]

226

78%

Impaired executive function (50%), impaired psychomotor coordination (57%)

[30]

1438

Dementia: 10% (at 6 months)–15% (at 12 months) MCI: 26.54% (at 6 months)–26.1% (at 12 months)

[31]

  1. The table includes some summaries of neurological involvement in COVID-19 patients in existing studies. The incidence of these symptoms varied with sample size and duration of observation. However, cognitive impairment and other neurological symptoms in COVID-19 patients cannot be ignored