Fig. 4
From: Immunoadsorption versus double-dose methylprednisolone in refractory multiple sclerosis relapses
Flow cytometry analysis of the B cell compartment. A Development of B cell subsets. Significance evaluated using the Mann–Whitney test. IA: 14 patients; MPS: 26 patients. B Development of B cell subsets in patients undergoing IA following two courses of MPS [8]. Boxes indicate median ± IQR and whiskers indicate range. Significance evaluated using Friedmann’s test including post-test. *: p < 0.05; *: p < 0.01. C association of treatment-related reduction in B cells with an increase in clinical function, assessed via MSFC, in patients with IA (n = 14) and MPS + IA (n = 8) using linear regression. MPS methylprednisolone, IA immunoadsorption, MSFC multiple sclerosis functional composite