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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: Investigation and modulation of interleukin-6 following subarachnoid hemorrhage: targeting inflammatory activation for cerebral vasospasm

Fig. 10

Downstream cascades were upregulated following SAH, but were reduced with p-STAT3 blockade on post-SAH day 7. A significant increase was seen in NFΚB following SAH (p < 0.001), which was reduced with p-STAT3 blockade (p < 0.001) (A). A significant increase was seen in TLR4 following SAH (p < 0.001), with reduction by p-STAT3 blockade (p < 0.001) (B). A significant increase in nitrotyrosine was seen following SAH (p < 0.001), with reduction by p-STAT3 blockade (p < 0.001), but not complete restoration to control levels (p < 0.05) (C). *comparison to saline. #comparison to SAH. Scale bar = 40 μm

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Journal of Neuroinflammation

ISSN: 1742-2094