Skip to main content
Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Ultrastructural characterization of dark microglia during aging in a mouse model of Alzheimer’s disease pathology and in human post-mortem brain samples

Fig. 1

Distribution and density of dark vs typical microglia. Density analysis based on ultrastructural characteristics of dark (DM) and typical microglia (TM) in the ventral hippocampus CA1 stratum lacunosum-moleculare of 20-month-old and age-matched C57BL/6J male mice. The density of TM (A) and DM (B) is shown. The density of microglia based on their proximity to plaques (far or near) as well as their state (TM or DM) is provided (C). The percentage of DM over all the microglia far from plaques or near plaques is represented in D. Data shown are expressed as means ± S.E.M. *p < 0.05, **p < 0.01, using a Kruskal–Wallis test with a post hoc Dunn’s multiple comparisons test. n = 4 animals

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094