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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Impaired response of blood neutrophils to cell-death stimulus differentiates AQP4-IgG-seropositive NMOSD from MOGAD

Fig. 4

Spontaneous and PMA-induced generation of MPO-DNA by AQP4 + NMOSD and MOGAD neutrophils. MPO-DNA complexes were analyzed by ELISA in neutrophil culture supernatants from AQP4 + NMOSD and MOGAD patients and HC. Unstimulated (black dots; none) and PMA-stimulated samples (red dots) are shown. Each dot represents an individual subject. Lines connect the unstimulated and PMA-stimulated data points of the same patient. None (unstimulated-vehicle). HC: n = 5; AQP4 + NMOSD: n = 11; MOGAD: n = 8

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Journal of Neuroinflammation

ISSN: 1742-2094