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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Alzheimer’s disease-related transcriptional sex differences in myeloid cells

Fig. 2

Sex differences in the transcriptome of aged ex vivo monocytes. A, B Dot plots showing the enriched gene ontology biological processes in the significantly sDEG upregulated in the nuclei of A F-MC (blue) and B M-MC (red). Significance of sDEG was determined via MAST analysis using an FDR < 0.05. C Bar chart showing the enrichment of IR-AD gene sets. A negative log fold change (logFC) denotes enrichment in F-MCs whilst a positive logFC denotes enrichment in M-MCs. D Correlation of the gene set enrichment scores for all IR-AD gene sets significantly enriched in the female samples with age. These data were derived from the re-analysis of the publicly available microarray data set E-GEOD-56047

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