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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Treadmill exercise promotes E3 ubiquitin ligase to remove amyloid β and P-tau and improve cognitive ability in APP/PS1 transgenic mice

Fig. 2

Effect of treadmill exercise on pathological characteristics of wild-type and APP/PS1 transgenic mice. A Immunofluorescence images showing Aβ plaques in the hippocampus of mice and statistical analysis of its data (n = 3 for each group). B Western blotting of Aβ and statistical analysis of its data (n = 6 for each group). C Statistical data showing the effect of exercise on hippocampal Total tau mRNA in each group of mice. D Western blotting of hippocampal p-Tau/Thr181 and statistical analysis of its data (n = 6 for each group). E Western blotting of hippocampal p-Tau/Ser202 and statistical analysis of its data (n = 6 for each group). Values are presented as mean ± SEM. Statistically different from WTC, *P < 0.05, **P < 0.01. Statistically different from ADC, #P < 0.05; ##P < 0.01

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