Fig. 2

TBI causes changes in DC pool and functions at the sub-chronic phase. A Relative frequencies (left) and absolute numbers (right) of cDCs in the spleen of Sham (n = 4) and d7-TBI (n = 5) mice. Data are representative of two independent experiments. B Relative frequencies (left) and absolute numbers (right) of cDC1 subset in the spleen of Sham (n = 4) and d7-TBI (n = 5) mice. Data are representative of two independent experiments. C Relative frequencies (left) and absolute numbers (right) of cDC2 subset in the spleen of Sham (n = 4) and d7-TBI (n = 5) mice. Data are representative of two independent experiments. D Relative frequencies (left) and absolute numbers (right) of immature cDC subset in the spleen of Sham (n = 4) and d7-TBI (n = 5) mice. Data are representative of two independent experiments. E Relative frequencies (left) and absolute numbers (right) of pDC subset in the spleen of Sham (n = 4) and d7-TBI (n = 5) mice. Data are representative of two independent experiments. F Relative frequencies (left) and absolute numbers (right) of PDCA1⁻CD11c^high cDC subset in the spleen of Sham (n = 4) and d7-TBI (n = 5) mice. Data are representative of two independent experiments. G Relative frequencies (left) and absolute numbers (right) of cDCs in the BM of Sham (n = 4) and d7-TBI (n = 5) mice. Data are representative of two independent experiments. H Relative frequencies (left) and absolute numbers (right) of cDC1 subset in the BM of Sham (n = 4) and d7-TBI (n = 5) mice. Data are representative of two independent experiments. I Relative frequencies (left) and absolute numbers (right) of cDC2 subset in the BM of Sham (n = 4) and d7-TBI (n = 5) mice. Data are representative of two independent experiments. J Relative frequencies (left) and absolute numbers (right) of pDC subset in the BM of Sham (n = 4) and d7-TBI (n = 5) mice. Data are representative of two independent experiments. K Relative frequencies (left) and absolute numbers (right) of PDCA1⁻CD11c^high cDC subset in the BM of Sham (n = 4) and d7-TBI (n = 5) mice. Data are representative of two independent experiments. All data represent mean ± SEM. Two-tailed student’s t tests were used to assess statistical significance (*P < 0.05, **P < 0.01, *** P < 0.001, **** P < 0.0001)