Fig. 2
From: T-cells in human trigeminal ganglia express canonical tissue-resident memory T-cell markers
CD8 and CD4 T-cells recovered from human nervous tissue show tissue-specific and inter-individual differences in marker expressions. Mononuclear cells were isolated from paired peripheral blood (blood), normal appearing white matter (NAWM) and trigeminal ganglia (TG) of deceased brain donors (n = 8). a–c tSNE plot of combined flow cytometric data on paired blood-, NAWM- and TG-derived CD8 (left panel) and CD4 (right panel) T-cells. Data are grouped in colors to indicate origin specimen (a), origin donor (b), and HSV-1 infection status of TG donor: HSV-1 naïve (HSV-1−) and latently HSV-1-infected donors (HSV-1+) (c). d Absolute number of CD3+ T cells normalized to gram of TG in HSV-1− and HSV-1+ donors