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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Early effects of LPS-induced neuroinflammation on the rat hippocampal glycolytic pathway

Fig. 2

LPS induces astrocyte reactivity in the hippocampus. S100B and GFAP were measured by ELISA, and S100B gene expression was evaluated by RT-PCR. LPS reduced S100B gene expression at both times (B), without changes in protein content in the hippocampus (A) and elevation of S100B protein levels in the CSF (C). LPS raises GFAP immunocontent only at 6 h. LPS 6 h (euthanized at 6 h after LPS administration), LPS 24 h (euthanized at 24 h after LPS administration). Values are expressed as means ± standard error. Data were analyzed by ANOVA, followed by the Tukey test, assuming P < 0.05. * means significant increase, when compared to sham group (* P < 0.05, ** P < 0.01), # means significant decrease, when compared to sham group

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