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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Constitutively active microglial populations limit anorexia induced by the food contaminant deoxynivalenol

Fig. 7

CD11b + expression within the DVC of control and DON-treated animals. A Representative photomicrographs of CD11b and IBA1 labeling taken from coronal brainstem sections of mice treated with vehicle or DON. The white lines symbolize the border between the AP and the NTS. B Overlay photographs of CD11b and IBA1 labeling from coronal brainstem sections of mice treated with vehicle or DON. The white boxes in panels A indicated regions from which panels B originated. Insets illustrate the modification of microglial phenotype in response to DON treatment. Scale bars: 500 µm in A; 50 µm in B. AP: area postrema; cc: central canal; fs: funiculus separans; NTS: nucleus tractus solitarius. C. Quantification of CD11b labeling expressed in mean gray level in DVC subregions of control and DON-treated animals (12.5 mg/kg BW; ***p < 0.001)

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