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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: Fetuin-A alleviates neuroinflammation against traumatic brain injury-induced microglial necroptosis by regulating Nrf-2/HO-1 pathway

Fig. 10

PLX5622-mediated microglia depletion attenuates the effect of Fetuin-A in TBI mice. A H&E staining of hemispheres sections (n = 3). B, C Lesion volume (n = 5) and water content% (n = 5) were analyzed by statistical. D, E Neuron death measured by TUNEL staining. Scale bar is 50 μm (n = 3). F A schematic diagram showing the neuroprotective and anti-inflammation effects of Fetuin-A. Data are presented as the means ± SD; &P < 0.05 vs. CCI + Veh group, and n.s.: no significant difference

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