Fig. 10

OPG concentration increases in CSF samples from human TBI patients. A Significant increase in osteoprotegerin (OPG) levels in cerebrospinal fluid (CSF) of TBI patients upon admission (CTR vs D0; 313.0 ± 46.1 pg/ml vs 467.5 ± 241.0 pg/ml) and 1d after trauma (CTR vs D1; 313.0 ± 46.1 pg/ml vs 524.1 ± 244.3 pg/ml). OPG levels decreased subsequently 3d (CTR vs D3; 313.4 ± 46.1 pg/ml vs 380.7 ± 229.6 pg/ml) and 7d (CTR vs D7; 313.4 pg/ml vs 403.6 ± 297.3 pg/ml) after trauma. Data are shown as mean ± SD. CTR N = 6; D0 N = 18; D1 N = 18; D3 N = 16; D7 N = 16. See Table 1 for clinico-demographic parameters. *p < 0.05; **p < 0.01