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Table 2 Immunological cells in the blood of EAE mice at disease onset

From: Peripheral myeloid-derived suppressor cells are good biomarkers of the efficacy of fingolimod in multiple sclerosis

 

Vehicle

FTY720

p value

% CD3+/Total blood cells

12.94 ± 1.32

16.77 ± 1.63

ns

% CD4+/Total blood cells

8.09 ± 0.77

10.91 ± 1.03

 < 0.05

% CD8 /Total blood cells

3.32 ± 0.30

4.42 ± 0.51

ns

% Ly-6Chi/Total blood cells:% CD3+

0.47 ± 0.13

0.39 ± 0.10

ns

% Ly-6Chi/Total blood cells:% CD4+

0.72 ± 0.19

0.58 ± 0.15

ns

% Ly-6Chi/Total blood cells:% CD8+

1.83 ± 0.55

1.68 ± 0.50

ns

% Ly-6Chi/Myeloid cells:% CD3+

0.58 ± 0.16

0.50 ± 0.13

ns

% Ly-6Chi/Myeloid cells:% CD4+

0.89 ± 0.23

0.75 ± 0.18

ns

% Ly-6Chi/Myeloid cells: % CD8+

2.25 ± 0.65

2.15 ± 0.62

ns

  1. The data are expressed as the mean ± SEM. The result of the Student’s t-test or a non-parametric Mann–Whitney test is shown: ns not significant
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Journal of Neuroinflammation

ISSN: 1742-2094