Fig. 7
From: Genetic deletion of Krüppel-like factor 11 aggravates traumatic brain injury
KLF11 genetic deletion increases TBI-induced infiltration of peripheral neutrophils and macrophages. KLF11 KO and WT mice were subjected to TBI or sham operation and the peripheral infiltration of neutrophils and macrophages was assessed by double-immunostaining in brain sections 3 d after operation. A Representative images of NeuN (green), Ly-6B (red, a marker of neutrophils), and DAPI (blue) immunostaining in peri-lesional brain regions. Rectangles: enlarged area of low-magnification images. B Quantitative analysis of Ly-6B-positive neutrophils from peri-lesional brains or sham mouse brains. C Representative images of F4/80 (green) and DAPI (blue) immunostaining in peri-lesional brain regions. Rectangles: enlarged area of low-magnification images. D Quantitative analysis of F4/80-positive macrophages/microglia from peri-lesional or sham mouse brains. Data are presented as mean ± SD, n = 6/group. Statistical analyses were performed by one-way ANOVA with Tukey’s post hoc test. *p < 0.05, **p < 0.01 or ***p < 0.001 versus TBI + WT group