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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: MyD88-TLR4-dependent choroid plexus activation precedes perilesional inflammation and secondary brain edema in a mouse model of intracerebral hemorrhage

Fig. 4

Dextran extravasation and inflammatory protein expression after striatal whole-blood injection. A Methodological steps of the semi-automated quantification of spatial protein expression (n = 21). B FITC-Dextran (70 kDa) average-intensity-maps at different time points with perilesional zoom-in. C Temporal dynamics of the mean leakage area for different dextrans (155 kDa, 70 kDa, 10 kDa). D CD45 average-intensity-maps at different time points with a CP/perilesional zoom-in. The arrow at 96 h indicates the high perilesional CD45 signal intensity. E Temporal dynamics of the mean CD45 signal intensity in different anatomical compartments. LV lateral ventricle, 3rdV third ventricle. F ICAM1 average-intensity-maps at different time points with CP zoom-in. G Temporal dynamics of the mean ICAM1 signal intensity in different anatomical compartments

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