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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Recombinant human plasma gelsolin reverses increased permeability of the blood–brain barrier induced by the spike protein of the SARS-CoV-2 virus

Fig. 4

Plasma gelsolin improves migration of hCMEC/D3 upon SARS-CoV-2 Spike protein S1 subunit treatment in wound-healing assay. Images of endothelial cells in a wound healing setting (Panel A), the yellow color indicates wound width, which is quantitatively shown in Panel B. Western blot quantitative analysis of VEGRF2 expression in hCMEC/D3 cells after 24 h stimulation with pGSN, S1, and S1 + pGSN (Panel C). The data represent the mean ± SEM of four independent experiments (n = 4). * and ^ indicate statistical significance at p ≤ 0.05 compared to CT (100%) and S1, respectively, by one-way ANOVA and Tukey post hoc test

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Journal of Neuroinflammation

ISSN: 1742-2094