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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Recombinant human plasma gelsolin reverses increased permeability of the blood–brain barrier induced by the spike protein of the SARS-CoV-2 virus

Fig. 6

Spike protein S1 subunit selectively decreases cell junction proteins in endothelial cells, forming a blood–brain barrier. Western blot bands (Panel A) and protein expression fold change (Panel B). The data represent the mean ± SEM of four independent experiments (n = 4). * and ^indicate statistical significance at p ≤ 0.05 compared to CT (100%) and S1, respectively, by one-way ANOVA and Tukey post hoc test

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