Table 1 Statistical analysis of cytokine levels in blood serum
Serum cytokine statistics | ||||||
|---|---|---|---|---|---|---|
Analyte | Interaction F(df) | Interaction p | Treatment F(df) | Treatment p | Drug F(df) | Drug p |
IL-1a | F [1, 37] = 0.0622 | 0.8044 | F [1, 37] = 0.4667 | 0.4987 | F [1, 37] = 4.029 | 0.0521 |
IL-5 | F [1, 33] = 3.211 | 0.0823 | F [1, 33] = 66.26 |  < 0.0001 | F [1, 33] = 4.107 | 0.0509 |
IL-6 | F [1, 33] = 25.27 |  < 0.0001 | F [1, 33] = 128.4 |  < 0.0001 | F [1, 33] = 15.49 | 0.0004 |
G-CSF | F [1, 33] = 5.129 | 0.0302 | F [1, 33] = 26.77 |  < 0.0001 | F [1, 33] = 0.0033 | 0.9544 |
IP-10 | F [1, 36] = 1.409 | 0.243 | F [1, 36] = 13.63 | 0.0007 | F [1, 36] = 4.530 | 0.0402 |
MKC | F [1, 33] = 13.57 | 0.0008 | F [1, 33] = 69.78 |  < 0.0001 | F [1, 33] = 4.587 | 0.0397 |
MCP-1 | F [1, 35] = 0.3542 | 0.5556 | F [1, 35] = 29.38 |  < 0.0001 | F [1, 35] = 0.0068 | 0.9345 |
Bonferroni–ŠÃdák post-hoc analysis | ||||||
|---|---|---|---|---|---|---|
Analyte | SV vs. BV | SN vs. BN | SV vs. SN | BV vs. BN | SV vs. BN | BV. vs. SN |
IL-1a | 0.9913 | 0.9997 | 0.7906 | 0.5126 | 0.9334 | 0.3124 |
IL-5 | < 0.0001 | < 0.0001 | > 0.9999 | 0.0492 | 0.0015 |  < 0.0001 |
IL-6 | < 0.0001 | 0.0001 | 0.9713 | < 0.0001 |  < 0.0001 |  < 0.0001 |
G-CSF | 0.0002 | 0.1603 | 0.5254 | 0.538 | 0.0057 | 0.0048 |
IP-10 | 0.02 | 0.2843 | 0.1666 | 0.9831 | 0.002 | 0.8327 |
MKC | < 0.0001 | 0.0068 | 0.8776 | 0.0011 | 0.0011 |  < 0.0001 |
MCP-1 | 0.0208 | 0.0002 | 0.9981 | 0.9994 | 0.0048 | 0.0018 |