Fig. 5

Overexpression of circ_0001293 alleviates IL-1β-induced astrocyte inflammation by downregulating miR-8114. a, b RT–qPCR was used to determine the expression of circ_0001293 and miR-8114. c Cell viability was detected using the CCK-8 assay. d ELISAs were conducted to determine the levels of TNF-α, IFN-γ, IL-6, IL-10 and TGF-β2. ^**P < 0.01 and ^***P < 0.001 compared with NC; ^##P < 0.01 and ^###P < 0.001 compared with IL-1β; ^&&&P < 0.001 compared with IL-1β + oe-circ. All values are presented as the means ± SD (n = 3)