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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Scorpion venom peptide HsTx2 suppressed PTZ-induced seizures in mice via the circ_0001293/miR-8114/TGF-β2 axis

Fig. 6

Inhibition of miR-8114 alleviates IL-1β-induced astrocyte inflammation by targeting TGF-β2. a, b RT–qPCR was used to determine the expression of miR-8114 and TGF-β2. c Cell viability was detected using the CCK-8 assay. d ELISAs were conducted to determine the levels of TNF-α, IFN-γ, IL-6, IL-10 and TGF-β2. ***P < 0.001 compared with NC; ###P < 0.001 compared with IL-1β; &&&P < 0.001 compared with IL-1β + miR-8114 inhibitor. All values are presented as the means ± SD (n = 3)

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