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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Parabiosis reveals the correlation between the recruitment of circulating antigen presenting cells to the retina and the induction of spontaneous autoimmune uveoretinitis

Fig. 2

Quantification of retinal immune cells in SAU. A, B Retinal T cell and myeloid cell counts in control R161H−/− × B6/J F1 (B10.RIII × B6/J F1) mice. Mean ± SD of retinal myeloid cells for mice ≤ 50 days of age indicated. Mean number of T cells and myeloid cells as function of age indicated by blue and red lines. C, D Kinetics of immune cell expansion in R161H+/− × B6/J F1 mice. Prophase, active, and resolving phases of SAU are indicated. Mean ± SD of myeloid cells in prophase with statistical comparison (t test) to ≤ 50 day old control mice is indicated. For comparison, the mean number of myeloid cells in control B10.RIII × B6/J F1 retinas (from B) has been reproduced in D (red line). Myeloid cells were defined as CD45medCD11b+Ly6Gneg and T cells were defined as CD45hiCD90.2+Ly6GnegCD49neg. Cell numbers determined by flow cytometry

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