Skip to main content
Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Parabiosis reveals the correlation between the recruitment of circulating antigen presenting cells to the retina and the induction of spontaneous autoimmune uveoretinitis

Fig. 4

Analysis of myeloid and T cells in the retina during SAU prophase. A Flow cytometry gating strategy of a representative R161+/− × CD11cDTR/GFP F1 retina. CD45+Ly6G cells (top right panel) were divided into four populations based on their CD45 vs. SSC-H profile with each population then analyzed for T cells and myeloid cells. BD Counts of retinal myeloid cells (CD11b+GFPhi and CD11b+GFPlo cells) and T cells from R161H+/− × CD11cDTR/GFP F1 (closed circles) and control B10.RIII × CD11cDTR/GFP F1 mice (open circles). Numbers presented as mean ± SD, n = 6. Statistical comparison of R161H+/− × CD11cDTR/GFP F1 and control B10.RIII × CD11cDTR/GFP F1 mice for each cell population is indicated (* = ρ < 0.01, ns = not significant by t test). Fold increase of total GFPhi myeloid cells versus total GFPlo myeloid cells in R161H+/− × CD11cDTR/GFP F1 and control B10.RIII × CD11cDTR/GFP F1 mice is indicated (4.85× vs. 1.72×, ρ = 0.002 by t test)

Back to article page