Skip to main content

Table 1 Top five differentially regulated canonical pathways in X-ALD macrophages

From: Saturated very long-chain fatty acids regulate macrophage plasticity and invasiveness

Term

Overlap

p value

Adjusted p value

Inflammatory response (GO:0006954)

78/230

2.59E−07

0.001396

Regulation of T cell proliferation (GO:0042129)

33/76

2.08E−06

0.005601

L-serine metabolic process (GO:0006563)

9/10

3.68E−06

0.00659

Cholesterol biosynthetic process (GO:0006695)

19/35

5.84E−06

0.006709

Sterol biosynthetic process (GO:0016126)

20/38

6.24E−06

0.006709

  1. Top 5 enriched GO Biological Processes with genes found to be differentially expressed between macrophages derived from X-ALD patients and healthy controls (n = 9 each). Adjusted p-values were calculated using Benjamini and Hochberg method
Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094