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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response

Fig. 3

Susceptibility to ZIKV infection is correlated with the inability of PCNs to stop viral replication. PCNs from non-susceptible CC001 and susceptible CC071 immunocompetent mice were either non-infected (NI) or ZIKV-infected at a MOI of 5. Levels of ZIKV RNA and of RNAs coding for IFNB and ISGs were analyzed by RT-qPCR with respect to Rplp0 used as reference gene. Symbols represent values obtained from n = 3 and 2 independent experiments for CC001 and CC071, respectively. Bars represent means

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