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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Fecal microbiota transplantation and replenishment of short-chain fatty acids protect against chronic cerebral hypoperfusion-induced colonic dysfunction by regulating gut microbiota, differentiation of Th17 cells, and mitochondrial energy metabolism

Fig. 2

FMT and SCFAs treatment ameliorate CCH-induced gut microbial dysbiosis. A Analysis of alpha diversity by shannon index and observed_species. B Analysis of beta diversity by non-metric multi-dimensional scaling (NMDS). C Relative abundance of top 10 gut microbiota at the genus level. D Heatmap based on nonparametric Wilcoxon test by MetaStat showing relative abundance of gut microbiota at the genus level. E Analysis of significant difference in abundance of gut bacteria by Linear discriminant analysis (LDA) coupled with effect size (LEfSe). Data are expressed as mean ± SD (n = 8 per group). *P < 0.05 vs. sham group. #P < 0.05 vs. BCCAo group

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