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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Lactate attenuates astrocytic inflammation by inhibiting ubiquitination and degradation of NDRG2 under oxygen–glucose deprivation conditions

Fig. 4

NDRG2 knockdown upregulates inflammatory pathways in OGD. A KEGG analysis of the upregulated DEGs induced by NDRG2 silencing in astrocytes predicts inflammation-associated canonical pathways. B KEGG analysis of the corresponding downregulated DEGs predicts inhibition of metabolism-associated canonical pathways. C The Cytoscape plugin ClueGO was used for KEGG pathway enrichment analysis and for determining clusters of signaling pathways. Area refers to the frequency of terms in the cluster. The terms are grouped into seven clusters. ClueGO was used to assess gene ontology and screen the central nodes

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Journal of Neuroinflammation

ISSN: 1742-2094