Fig. 7

Venn diagram of colonic microorganisms OTU number, α diversity and β diversity responses in the colon of CUMS mice. a Venn diagram showing the number of OTUs in the WT Control, WT CUMS,TPH2 KO Control,TPH2 KO CUMS and WT CUMS + FLX groups. b Statistics for the four groups. The α diversity includes diversity and richness. c Shannon curves, d OTU rank curves, e Rank abundance curve, f Shannon index, g Simpson index of WT Control, WT CUMS, TPH2 KO Control, TPH2 KO CUMS and WT CUMS + FLX. The β diversity shows the dispersion of each sample in the WT Control, WT CUMS, TPH2 KO Control, TPH2 KO CUMS and WT CUMS + FLX groups. h Principal component analysis (PCA), i Nonmetric multidimensional scaling (NMDS) score plot based on the Bray–Curtis score plot based on the OTU in the colon. Values are presented as the means ± SEM. WTC: WT Control, WTS: WT CUMS, KOC: TPH2 KO Control, KOS: TPH2 KO CUMS, Treat: WT CUMS + FLX