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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Nanoparticulate MgH2 ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress

Fig. 2

Behavioral changes occur in EAE mice and can be improved by MgH2. A Schematic diagram displaying the behavioral test protocol used in the study. B Open field test (OFT), statistical analysis of total distance (F = 20.9005), time (F = 3.4964) and entries (F = 3.4233) in the central area, n = 8 mice per group. C Marble burying test (MBT), statistical analysis of the number of buried marbles (F = 0.2692), n = 5 mice per group. D Light/dark transition test (LDT), statistical analysis of time in the light chamber (F = 4.4714) and transition numbers (F = 3.9609), n > 7 mice per group. E Sucrose preference test (SPT), statistical analysis of the percentage of sucrose consumption (F = 10.4649), n = 5 mice per group. F Tail suspension test (TST), statistical analysis of immobile time (F = 7.5058), n = 7 mice per group. Data are presented as mean ± SEM

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