Fig. 8
From: Role of acyl-coenzyme A: cholesterol transferase 1 (ACAT1) in retinal neovascularization
ACAT1 inhibition decreases expression of ACAT1 and inflammatory mediators. OIR mice were treated with K604 or vehicle from P7 to P16. Retinal lysates were prepared at P17 for Western blotting. a Representative western blots and b–f their quantification shows that ACAT1 inhibition significantly suppresses expression of MCSF (a, b), ACAT1 (a, c), TREM1 (a, e), and LDLR (a, f), as compared with the vehicle control. However, K604 treatment did not alter levels of VEGF (a, d). mean ± SEM, n = 6